Bioreactor
CellBios® Bioreactor is a single use reactor bag used for simple cell culture, biomass production and as large-scale open systems. It is made up of multi (5) layered PE film (CSF514).
Ranging from 1 L to 50 L
CellBios® is one of the leading companies in the world to offer bioreactors in 6 different configurations from 1 L to 50 L. Further options are available through our custom order process through which we can accommodate most end user’s process needs.
FEATURES
- Specially designed for easy fluid handling
- Excellent durability and toughness
- Highly sealable and weldable to provide leak resistance
- Exhibits superior clarity and transparency for good visibility
- Excellent gas barrier properties
- Reduces the risk of cross-contamination
- Suitable for long term storage of materials at a wide range of pH and temperatures
BENEFITS
Reduced cost:
Eliminating filters lead to significant cost savings, especially for large-scale operations.
Increased efficiency:
Bioreactors without filters can achieve higher yields of product desired.
Simplified design:
Beneficial for low-tech or resource- limited settings.
Continuous processing:
Eliminates the need for separate harvesting steps and simplifies the overall process.
| S.No | Specification |
|---|---|
| 1 | MPC coupling plug |
| 2 | MPC coupling body |
| 3 | TPE tube |
| 4 | Pinch clamp |
| 5 | Female luer with cap |
| 6 | Needle-free site |
| 7 | Slide clamp |
| 8 | Air inlet vent filter |
| 9 | Disc port connector |
| 10 | Check valvehose barb |
| S.No. | Description |
|---|---|
| Filter pore size | 1.2µm |
| Tube length | 5 cm to 200 cm |
| Tube diameter (ID x OD) | 6.4 x 9.5 mm (1/4 x 5/8 in.) |
| Disc port | 6.4 mm, 9.5 mm, 12.7 mm |
| Connector | 19.05 mm, 25.4 mm |
APPLICATIONS
Inoculation and cell culture: Inoculation of a culture medium with the desired cells, such as yeast, bacteria, or mammalian cells in the bioreactor bag. Cells grow and multiply in the bioreactor bag under controlled conditions.
Controlled environment: Bioreactor bags provide a controlled environment for cell growth, including parameters like pH, temperature, nutrient availability and dissolved oxygen. These parameters are important for maximizing product quality and cell productivity.
Product formation: When the cells grow and metabolize nutrients, they produce the desired product, which could be antibiotics, enzymes, proteins, or biofuels.
Downstream processing: Purification, concentration, and formulation to produce the final product in a purified and stable form.
Monoclonal Antibodies (mAbs): Bioreactor bags are used to produce large quantities of mAbs by culturing mammalian cells expressing the desired antibody to treat cancer and various autoimmune diseases.
Recombinant protein production: To produce, growth factors, insulin and other hormones.
Vaccine production: Bioreactor bags are used to produce viral vaccines, recombinant subunit vaccines, and other types of vaccines for preventing infectious diseases.
Cell expansion: Bioreactor bags are used to expand and grow therapeutic cells (stem cells/ immune cells). The controlled environment in the bioreactor bag ensures optimal cell growth.
Gene Delivery: Bioreactor bags are used for gene delivery and genetic modification of cells.
CGT and immune therapy: Stem cells, CAR-T cells, NK cells and several other immune cells are cultured using CellBios® Bioreactor Bag.
Ordering Information
| Part Number | Product Description | Volume | Working Volume | Outer Bag Size WXL (mm) | Inner Bag Size WXL (mm) |
|---|---|---|---|---|---|
| 2DBRBA-01 | Bioreactor Bag 1 L | 1 L | 500 mL | 292 x 575 | 272 x 265 |
| 2DBRBB-01 | Bioreactor Bag 2 L | 2 L | 1 L | 292 x 575 | 272 x 415 |
| 2DBRBC-01 | Bioreactor Bag 5 L | 5 L | 2.5 L | 365 x 565 | 345 x 405 |
| 2DBRBD-01 | Bioreactor Bag 10 L | 10 L | 5 L | 365 x 565 | 345 x 445 |
| 2DBRBE-01 | Bioreactor Bag 20 L | 20 L | 10 L | 625 x 710 | 605 x 586 |
| 2DBRBF-01 | Bioreactor Bag 22 L | 22 L | 11 L | 500 x 870 | 480 x 750 |
| 2DBRBG-01 | Bioreactor Bag 50 L | 50 L | 25 L | 760 x 870 | 740 x 750 |
